Chrome has implemented a built-in print dialog that, by default, gives you a preview of your print job in a new tab and handles all of your printing needs without going through your operating system's default print dialog.
It's a nice feature when it works, but in practice, the preview crashes — a lot — and when it does, the Print button is disabled. Here's how to work around Chrome's crashy print dialog so you can still get your print on when necessary.
Click the Advanced or Print using link: If you're using the beta or stable channel of Chrome, currently your only recourse is to go through Chrome's standard print dialog, let the print preview crash, and then click the Advanced link at the bottom of the lefthand sidebar (that link text changes to Print using system dialog in the dev channel). Clicking Advanced just opens your operating systems default print dialog.
Press Ctrl+Shift+P (Cmd+Shift+P on OS X): Currently available in the most recent version of Chrome's dev channel (which means it'll likely be in Chrome's beta and stable releases eventually), this shortcut skips Chrome's print dialog and opens you're system's standard print dialog.
As you can see, it's pretty simple if you know where to look. I've been having a lot of trouble with it lately, and I've heard complaints from others, so it seemed like a workaround others might be interested in. Hopefully the Chrome team will get this fixed up in time, because when it works, it really is a convenient feature.