Chrome: You can search any site or alternative search engine by just creating a search shortcut in Chrome, but that imposes a number of limitations on your search. If you prefer the powered up search engine DuckDuckGo but love Google Chrome, their extension offers a more robust way to find what you're looking for.
The DuckDuckGo extension requires a click in the toolbar to access its search options, so it isn't perfect. That said, it automatically integrates its Instant Answers feature to your search queries on Google and Bing, provides search shortcut suggestions (which DDG calls bangs), and allows you to easily manage your search settings. DDG promises more features in the future, but fans of the site and Google Chrome should appreciate its current offering as well.
DuckDuckGo for Chrome [Chrome Web Store]