If you happen to be incredibly clumsy and spill food or drinks inside your refrigerator all the time, Reddit user Thinkadinky suggests you line the shelves with plastic wrap for simple, one-step cleaning.
Use a plastic wrap with a sealant on it and lay the wrap across your shelves. If the shelves get coated in food or an exploded drink, you simply remove the wrap. No real cleaning is required. It's probably the most useful for the clumsiest among us who are constantly spilling everything in a fridge, but it might come in handy if you know you're storing something that nearly always causes a mess or leaks. If you have wire shelves, you can use the same idea to create a makeshift shelf and prevent cross contamination of food.