Mac only: We like Simplenote for its simplicity, and the head honcho here considers it the Holy Grail of text capture. But not everyone loves the desktop options, or the website design. Split the difference with a single-site Fluid app for Simplenote and a deliciously cleaned-up style.
In other words, Ryan James' crafty CSS file for Simplenote cleans up the site in a way reminiscent of Simplenote's iPad version, and even offers a better dock icon. You'll need to install Fluid and customise it with James' files to get the style, but it looks like a great option for those who take notes regularly throughout their workday.
Simplenote Fluid userstyle [Ryan James]