Adobe just released a beta of the newest Flash player, complete with lower CPU usage and full screen dual-monitor playback. Chrome, though, still uses its built-in, stable version of Flash. Here's how to get the beta goodies in Chrome.
Even after installing the 10.2 beta, Chrome will default to its built-in version of Flash, even though it detects the 10.2 beta just fine. To use the beta instead of the stable version, open up Chrome and type
about:plugins in the address bar. Hit the "Details" button in the upper-right hand corner, and under "Flash" you should see two different plugins — one in Chrome's folder, and one elsewhere (see above). Hit Disable under the one located in Chrome's folder, and close out of the plugins window. To see if it worked, you can try watching Adobe's Stage Video demo.
If it works, you're using the beta. If it tells you to install the beta, go back to about:plugins and make sure you've disabled the correct plugin. Once you get the beta working, you should notice Flash hogs less of your CPU, and can play videos in full screen on one monitor while you work on the other!
How-To: Disable Chrome's Built-In Flash to Use a Flash Beta Release [Download Squad]