One of the minor annoyances of the revamped Twitter design is that it makes searching for individual Twitter users a multi-click affair (you search first and then specify that it's a person you're looking for). You can avoid that inconvenience by setting up a keyword bookmark instead.
We've walked through the process of setting up keyword bookmarks before, and noted that it's also possible for Chrome as well as Firefox. Simply use the address http://twitter.com/#!/search/users/%s for the bookmark, and set whatever keyword you like for it (I chose tp). The result? A people search that doesn't require you to ever take your hands off the keyboard.