I hardly ever use the safes in hotel rooms, and one major reason is that they're rarely large enough to fit even a moderately-sized notebook PC. The hotel room I've been staying in this week not only solves that problem, but adds something even more useful to the internals of the safe: a power outlet.
While the in-room safe at the Langham Place Mongkok Hotel in Hong Kong might not take a really large machine, it is big enough to take the size of PC any regular traveller would have. (As I've noted before, extra-large laptop screens are not travel-friendly even if they do make DVD watching more pleasurable.)
More importantly, the built-in adaptor slot means you can leave your device charging while you're out exploring the town: a good way to make use of your in-room power without risking leaving your PC out when the room gets cleaned.