Windows only: Megaupload Downloader retrieves and batches downloads from file-sharing sites like Megaupload, Rapidshare, MediaFire and more by copying and pasting links. The program will also download videos from video sites like YouTube and Veoh.
Like previously mentioned RapGet, Megaupload Downloader makes downloading files from file-sharing services easier but supports a larger variety of sources. Best of all, it is a resource-light program. You'll have to change the default language to English from Italian upon startup, but the program is simple and intuitive. Megaupload Downloader is a free download for Windows only.