Windows Live Writer, pretty much our favourite Windows Live application, can be run from a thumb drive, and it can even incorporate all the settings and sites you've already set up on your existing Live Writer setup.
How-to blog Online Tech Tips details the use of Windows Live Writer Portable to create a portable app to be run off a USB drive, a network drive or any other storage space. If you're already running Live Writer, the portable tool will ask you to point to it on your hard drive, and then pick up your setup from there. If you're planning on being away from your laptop, but still need to update or manage a site, you can do much worse than a portable Live Writer setup.
Use Windows Live Writer from a USB Drive [Online Tech Tips]