Windows only: If all you really want out of your iPod experience is the ability to load music, movies and podcasts onto your iPod without any bulk or bloat, portable and free CopyTransManager is a speedy iTunes-alternative.
Click on the image above for a closer look.
You can use CopyTransManager to manage both your iPod, iPod Touch and iPhone. All major functionality, sans things like access to the iTunes stores and ripping CDs, is present in CopyTransManger. You can create and edit playlists, import artwork, edit track information, search and synchronise your music and even store CopyTransManager on your iPod to access it wherever you can access portable applications.
CopyTransManager is available as a stand-alone portable application or part of the CopyTrans Suite which includes CopyTrans (allows you to repopulate your iTunes library from your iPod) and CopyTrans Photo (photo syncing between your iPod and PC).
CopyTransManager is free, Windows only, and portable.