There's already more Twitter clients than you can poke a stick at, but if you want a unique way to check the latest tweets, good old Excel is another option.
Office Watch details how you can use Excel's built-in ability to read an RSS feed to get your Twitter updates straight into a spreadsheet. Granted, this is a seriously geeky way of going about something you can do from pretty much any browser, but if you live your work life in Excel, it might be worth considering, especially since it'll make it less obvious to your boss what you're doing. For power Twitter users, getting feeds into Excel also opens up all kinds of analysis possibilities.
Not convinced you need Twitter at all? Check out our rundown of six ways you should be using Twitter.